The Cannondale Synapse Carbon 4 balances stiffness and comfort superbly, surprising me from the word go with its incredibly responsive frame. It’s good value, too, when you consider how future-proof it is, with wider tyre clearance than its rivals, giving it the ability to become an allroad gravel machine for adventures off the beaten path.

The all-new Synapse shares many of its design elements with the current SuperSix Evo. Cannondale even views the new Synapse on the same level as its race bike – and claims it melds WorldTour-level aerodynamics and stiffness with generous tyre clearance, compliance and features that appeal to the general rider.

Cannondale Synapse Carbon 4: Ride

I’ll admit I wasn’t expecting any fireworks from the Synapse in the performance department when it first arrived for testing, but it surprised me from the first ride. The handling feels a lot like the current SuperSix Evo, and there are hints of the SuperX in there, too, its race-focused gravel bike – particularly in the way it deals with vibrations and smooths out broken roads.

2025 Cannondale Synapse Carbon 4 3_4 view.jpg
2025 Cannondale Synapse Carbon 4 3_4 view (Image Credit: Farrelly Atkinson)

Cannondale says it has increased stiffness in the head tube and bottom bracket, while improving compliance by 20% over its predecessor to enhance overall performance. The frame is incredibly responsive, balancing stiffness and comfort superbly. Despite a longer wheelbase and chainstays, the Synapse is still pretty nimble, eager to respond to steering inputs, but still very predictable on descents and flowing sections of tarmac.

2025 Cannondale Synapse Carbon 4 headtube detail.jpg
2025 Cannondale Synapse Carbon 4 headtube detail (Image Credit: Farrelly Atkinson)

The stock 32mm tubeless-ready Rubino tyres are just brilliant. While converting the tyres to tubeless is a non-negotiable for me these days, I elected to use the stock wheel and tyre setup for the duration of my testing. Based on the bike’s weight, I didn’t drop the tyre pressures as much as I usually do for tube-type setups, but still went as low as 60psi for the front and 65 for the rear for my 62kg weight, which seemed to provide a good balance between comfort and speed.

2025 Cannondale Synapse Carbon 4  rear tyre clearance.jpg
2025 Cannondale Synapse Carbon 4 rear tyre clearance (Image Credit: Farrelly Atkinson)

Speaking of weight, it was only on very steep climbs of five minutes or more that I felt the full wrath of the 9kg, but for the most part I didn’t think the bike was holding me back – it carries momentum impressively well and maintains its speed very well. Thankfully, it’s been specced with a 50/34T chainring and 11-34T cassette, which ensure ample speed on the flats without crazy-high cadences, and a decent spread of gearing for when things get particularly steep.

2025 Cannondale Synapse Carbon 4 chainset.jpg
2025 Cannondale Synapse Carbon 4 chainset (Image Credit: Farrelly Atkinson)

Despite its alloy construction, the cockpit is well considered, and at 38mm wide represents a sweetspot in terms of balancing ergonomic performance with aerodynamics. While the stack and liberal stem spacers did raise my hand position and create a slightly more upright riding position than I’m used to, I very much enjoyed it thanks to the 381mm reach figure. You can still get fairly aero and not feel like the slightly more upright position is costing you – it feels natural and comfortable.

2025 Cannondale Synapse Carbon 4  front on.jpg
2025 Cannondale Synapse Carbon 4 front on (Image Credit: Farrelly Atkinson)

Cannondale Synapse Carbon 4: Frame

The new Synapse cuts a striking appearance and retains much of Cannondale’s current design DNA, with full integration taking centre stage. It bears a strong resemblance to the current SuperSix Evo, as evidenced by the narrow head tube, boxy down tube, top tube, and dropped seatstays.

2025 Cannondale Synapse Carbon 4 paint detail.jpg
2025 Cannondale Synapse Carbon 4 paint detail (Image Credit: Farrelly Atkinson)

Our Synapse Carbon 4 test bike might be one model up from the bottom of the range, but the richness of its Metallic Red paint scheme bolsters its perceived value with head-turning appeal (it’s also available in an off-white Chalk). It all looks very premium and refined.

2025 Cannondale Synapse Carbon 4 mounts.jpg
2025 Cannondale Synapse Carbon 4 mounts (Image Credit: Farrelly Atkinson)

The geometry numbers are not too far removed from the previous-generation Synapse. It has the same 570mm stack height and 381mm reach as before, but the head angle is down from 73 to 71.5 degrees. For context, the SuperSix Evo has a stack and reach of 555mm and 384mm, along with a 71.2-degree head angle.

All Synapse models come as standard with 32mm tyres, but there’s space at the rear for up to 42mm and the ability to go as wide as 48mm at the fork. It’s no gravel bike and doesn’t profess to be one, but I suspect some owners will attempt to shoehorn wider tyres than stated in the quest to create the ultimate allroad machine.

2025 Cannondale Synapse Carbon 4  front tyre clearance.jpg
2025 Cannondale Synapse Carbon 4 front tyre clearance (Image Credit: Farrelly Atkinson)

The increased tyre clearance has resulted in a 39mm increase in the wheelbase (1,026mm) and a 3mm increase in trail (61mm), as well as longer chainstays (up 15mm to 425mm), in size 54cm.

There are mounts for mudguards and a small top tube bag, to go with the usual bottle cage bosses inside the triangle, plus StashPort down tube storage under the bottle cage – the system already used on the Topstone Carbon.

2025 Cannondale Synapse Carbon 4 top tube storage bosses cover.jpg2025 Cannondale Synapse Carbon 4 top tube storage bosses.jpg2025 Cannondale Synapse Carbon 4 tyre.jpg2025 Cannondale Synapse Carbon 4 storage lid.jpg2025 Cannondale Synapse Carbon 4 storage 3.jpg2025 Cannondale Synapse Carbon 4 storage 2.jpg2025 Cannondale Synapse Carbon 4 rim detail.jpg2025 Cannondale Synapse Carbon 4 saddle.jpg2025 Cannondale Synapse Carbon 4 seatpost.jpg2025 Cannondale Synapse Carbon 4 rim and tyre.jpg2025 Cannondale Synapse Carbon 4 rear tyre clearance 2.jpg2025 Cannondale Synapse Carbon 4 rear brake caliper and rotor.jpg2025 Cannondale Synapse Carbon 4 name logo.jpg2025 Cannondale Synapse Carbon 4 paint detail.jpg2025 Cannondale Synapse Carbon 4 profile.jpg2025 Cannondale Synapse Carbon 4 mounts.jpg2025 Cannondale Synapse Carbon 4 headtube detail.jpg2025 Cannondale Synapse Carbon 4 front hub.jpg2025 Cannondale Synapse Carbon 4 chainrings.jpg2025 Cannondale Synapse Carbon 4 chainset.jpg2025 Cannondale Synapse Carbon 4 derailleur.jpg2025 Cannondale Synapse Carbon 4 BB.jpg2025 Cannondale Synapse Carbon 4 bar detail.jpg2025 Cannondale Synapse Carbon 4 3_4 view.jpg2025 Cannondale Synapse Carbon 4  handlebar.jpg2025 Cannondale Synapse Carbon 4  mounts 2.jpg2025 Cannondale Synapse Carbon 4  rear tyre clearance.jpg2025 Cannondale Synapse Carbon 4  front tyre clearance.jpg2025 Cannondale Synapse Carbon 4  front on.jpg2025 Cannondale Synapse Carbon 4  chainrings 2.jpg

It can store tools, a tube and a hand pump, freeing up your pockets. (SmartSense-equipped Synapses use this space to store the battery.)

2025 Cannondale Synapse Carbon 4 storage 3.jpg
2025 Cannondale Synapse Carbon 4 storage 3 (Image Credit: Farrelly Atkinson)

Cannondale Synapse Carbon 4: Finishing kit

As one of the lower-end models in the range, the Synapse 4’s specification list isn’t lavish but it is still well appointed. Bar the frame and Cannondale C1 Aero 27 seatpost, there’s not much in the way of carbon fibre componentry, but the alloy Vision Trimax Aero handlebar and Cannondale C1 Conceal stem are ideally suited for the job at hand, as is the Fizik Vento Argo X5 saddle.

2025 Cannondale Synapse Carbon 4  handlebar.jpg
2025 Cannondale Synapse Carbon 4 handlebar (Image Credit: Farrelly Atkinson)

The seatpost is shared with the SuperX, CAAD13 and SuperSiX Evo Gen 3. Unlike the previous edition, SmartSense (comprising an integrated front light, rear light, and rear radar with a battery in the down tube) is now only available on three of the eight models: the range-topping Lab71, Carbon 2, and Carbon 3.

2025 Cannondale Synapse Carbon 4 seatpost.jpg
2025 Cannondale Synapse Carbon 4 seatpost (Image Credit: Farrelly Atkinson)

In a move similar to the automotive industry, Cannondale has introduced part sharing across its drop-bar offerings, so the Synapse now features the same threaded BSA bottom bracket and Delta steerer first seen on the current SuperSix Evo, as well as the same thru-axles, rear hangers, and stems.

2025 Cannondale Synapse Carbon 4 BB.jpg
2025 Cannondale Synapse Carbon 4 BB (Image Credit: Farrelly Atkinson)

At the heart of the bike lies the rock-solid and proven Shimano 105 Di2 groupset, featuring sharp hydraulic braking and refined shifting. Sharing its basic architecture and functionality with Ultegra and Dura-Ace, it operates similarly to its pricier siblings, just with a slight weight penalty.

2025 Cannondale Synapse Carbon 4  chainrings 2.jpg
2025 Cannondale Synapse Carbon 4 chainrings 2 (Image Credit: Farrelly Atkinson)

The Synapse Carbon 4 employs a pair of rather heavy but durable alloy DT Swiss 470 rims. Wrapped in 32mm Vittoria Rubino Pro IV tyres, it’s all hardy rolling stock that brings peace of mind and reliability to the package.

2025 Cannondale Synapse Carbon 4 rim and tyre.jpg
2025 Cannondale Synapse Carbon 4 rim and tyre (Image Credit: Farrelly Atkinson)

Total system weight, however, is not the Synapse Carbon 4’s strong point – we’re talking 8.95kg without pedals. That said, there’s scope to cut the lard easily; new wheels, tyres, rotors and a carbon-railed saddle will drop the overall figure by as much as 1kg.

2025 Cannondale Synapse Carbon 4 saddle.jpg
2025 Cannondale Synapse Carbon 4 saddle (Image Credit: Farrelly Atkinson)

Cannondale Synapse Carbon 4: Value

Cannondale has done an incredible job with the new Synapse, and this is reflected throughout the range. It is relatively heavy, but this comes down to the alloy DT Swiss 470 rims, which can be sorted out easily if you’ve got a few bob lying about.

2025 Cannondale Synapse Carbon 4 rim detail.jpg
2025 Cannondale Synapse Carbon 4 rim detail (Image Credit: Farrelly Atkinson)

At £3,995 for a carbon-framed endurance bike, with Shimano 105 Di2 electronic shifting coming as standard, it’s cheaper than its nearest rivals.

The biggest of those comes in the form of the Canyon Endurace CF SLX 7 Di2. At £4,199, it is pricier than the Synapse, with the same Shimano 105 Di2 groupset, and though it gains carbon wheels – a wheelset upgrade that would significantly add to the price of the Synapse – its 35mm tyre clearance comes up significantly short.

Likewise, the Trek Domane SL6 Gen 4 might have better tyre clearance than the Endurace (38mm), but it can’t match the 42mm of the Synapse, nor its price – the Domane costs £4,175 in 105 Di2 spec. The Domane is also fairly heavy at 8.9kg, but again, this comes down to the aluminium wheels.

Read our guide to the best endurance road bikes for more options. 

Cannondale Synapse Carbon 4: Conclusion

The Synapse Carbon 4 is one of my favourite bikes of the year. It belies its nearly 9kg weight with its balanced geometry, aero-optimised carbon frame and well-sorted gearing. It took me by surprise, and probably will do many others, too. While there are better-specced Synapse models further up the range, I expect the Carbon 4 to be the volume seller and the bike that puts Cannondale back on the radar of the general rider.

Verdict

A belter of a bike with a price tag to match

All the deals displayed on our review pages are pulled from a constantly updating database feed of the best affiliate deals available. The criteria for deciding on what are the best deals is who is offering the lowest, delivered price. In most cases we will be showing the very best deal available online, but sometimes you may be able to find an item cheaper. If you can please feel free to post a link in the comments box below. To find out more about affiliate links on road.cc click here.

road.cc test report

Make and model: Cannondale Synapse Carbon 4

Size tested: 54

About the bike

List the components used to build up the bike.

Frame and fork: Carbon frame and fork, Proportional Response construction, integrated cable routing, downtube Stashport.

Groupset: Shimano 105 Di2

Chainset: Shimano 105 50/34T with 172.5 cranks

Cassette: Shimano 105 11-34T

Brakes: Shimano 105 7170 hydraulic disc, 160/160mm RT70 rotors

Wheels: DT Swiss R470

Tyres: Vittoria Rubino Pro IV 32mm

Handlebar: Vision Trimax Aero Alloy

Stem: Cannondale C1 Conceal, Alloy, 31.8, -6°

Grips: Cannondale Bar Tape, 3.5mm

Saddle: Fizik Vento Argo X5, 140mm

Seatpost: Cannondale C1 Aero 27 Carbon, SmartSense compatible

Tell us what the bike is for and who it’s aimed at. What do the manufacturers say about it? How does that compare to your own feelings about the bike?

Cannondale says the bike is for “comfortable high-performance road riding, long-distance missions, fast group rides”.

“Synapse Carbon 4 runs Shimano 105 Di2 for a shifting experience that feels straight off the pro tour, minus the bank loan. The frame delivers that signature Synapse ride quietly fast, endlessly composed, and plays nice with wide tires, fenders, and long days. Call it the sweet spot between Sunday speed and weekday practicality.”

Where does this model sit in the range? Tell us briefly about the cheaper options and the more expensive options

The Synapse Carbon 4 sits second from the bottom in the range. The Carbon 5 is the entry-level model, while the Synapse Lab71 SmartSense spearheads the eight-bike lineup.

Frame and fork

Overall rating for frame and fork
 
9/10

Tell us about the build quality and finish of the frame and fork?

The bike is built to a high standard and feels like it’s of a much higher price point.

Tell us about the materials used in the frame and fork?

The frame and fork are constructed from carbon fibre.

Tell us about the geometry of the frame and fork?

The geometry is not racy – it uses endurance angles to promote comfort and performance over long distances.

How was the bike in terms of height and reach? How did it compare to other bikes of the same stated size?

Stack and reach are spot on for this type of bike, hitting the sweetspot as far as endurance bikes go.

Riding the bike

Was the bike comfortable to ride? Tell us how you felt about the ride quality.

Yes. The ride quality is very comfortable, but this doesn’t affect performance and responsiveness.

Did the bike feel stiff in the right places? Did any part of the bike feel too stiff or too flexible?

Cannondale says it has increased stiffness in the head tube and bottom bracket, while improving compliance by 20% over its predecessor to enhance overall performance.

How did the bike transfer power? Did it feel efficient?

Yes.

Was there any toe-clip overlap with the front wheel? If so was it a problem?

No.

How would you describe the steering? Was it lively neutral or unresponsive? Neutral.

Tell us some more about the handling. How did the bike feel overall? Did it do particular things well or badly?

Handling is pretty sharp despite the longer wheelbase and chainstays, and this allows you to descend and corner with confidence thanks to the surefootedness provided by the wheelbase.

Which components had the most effect (good or bad) on the bike’s comfort? would you recommend any changes?

The wheels are not the greatest set out there. As alloy options, they are very heavy, but can be upgraded over time to improve acceleration, ride feel and comfort.

Which components had the most effect (good or bad) on the bike’s stiffness? would you recommend any changes?

An affordable pair of carbon wheels will not only drop the weight but also improve the performance and ride feel.

Which components had the most effect (good or bad) on the bike’s efficiency? would you recommend any changes?

The carbon frame, Shimano 105 Di2 groupset, and 38cm handlebar made for an exceptionally sharp and compliant machine.

Rate the bike for efficiency of power transfer:
 
8/10
Rate the bike for acceleration:
 
7/10
Rate the bike for sprinting:
 
7/10
Rate the bike for high speed stability:
 
8/10
Rate the bike for cruising speed stability:
 
8/10
Rate the bike for low speed stability:
 
8/10
Rate the bike for flat cornering:
 
8/10
Rate the bike for cornering on descents:
 
9/10
Rate the bike for climbing:
 
6/10

The drivetrain

Rate the drivetrain for performance:
 
8/10
Rate the drivetrain for durability:
 
8/10
Rate the drivetrain for weight:
 
7/10
Rate the drivetrain for value:
 
8/10

Wheels and tyres

Rate the wheels for performance:
 
6/10
Rate the wheels for durability:
 
8/10
Rate the wheels for weight:
 
5/10
Rate the wheels for comfort:
 
6/10
Rate the wheels for value:
 
8/10
Rate the tyres for performance:
 
8/10
Rate the tyres for durability:
 
9/10
Rate the tyres for weight:
 
7/10
Rate the tyres for comfort:
 
7/10
Rate the tyres for value:
 
7/10

Controls

Rate the controls for performance:
 
9/10
Rate the controls for durability:
 
9/10
Rate the controls for weight:
 
7/10
Rate the controls for comfort:
 
8/10
Rate the controls for value:
 
8/10

Your summary

Did you enjoy riding the bike? Yes

Would you consider buying the bike? Yes

Would you recommend the bike to a friend? Yes

How does the price compare to that of similar bikes in the market, including ones recently tested on road.cc?

The Cannondale Synapse Carbon 5 is the cheapest option among its closest rivals with Shimano 105 Di2 groupsets. Okay, the Canyon Endurace CF SLX 7 Di2 gets carbon wheels for its £4,199 RRP, but it lacks the tyre clearance of the Synapse. The same goes for the £4,175 Trek Domane SL6 Gen 4: it also has alloy wheels, and the spec is the same, but the tyre clearance is not as generous as the Cannondale.

Rate the bike overall for performance:
 
8/10
Rate the bike overall for value:
 
7/10

Use this box to explain your overall score

I think Cannondale has done an incredible job with the new Synapse: it’s stiff but comfortable, nimble when you want it to be but also predictable. It’s also a little cheaper than rivals with the same groupset, but what really sets it apart is the extra tyre clearance, adding versatility and future-proofing to the mix. Overall, it’s excellent.

Overall rating: 9/10

About the tester

Age: 0  Height: 175cm  Weight: 62kg

I usually ride:   My best bike is:

I’ve been riding for: 10-20 years  I ride: Every day  I would class myself as: Semi pro

I regularly do the following types of riding: road racing, time trialling, mtb, Time trial, gravel and Elite Cycling eSports