I had my first ever pinch flat the other day, and it wasn't a snakebite.
Ultegra wheels, riding new Conti 4000s II 25c at around 90psi on the rear (80 front). Instead of rim tape, the Ultegra have this deep channel in the middle of the rim, and when I fitted the tubes, I wondered if it put them under extra stress.
I hit a rock doing doing 20mph-ish. My first thought was that I'd ripped the tyre, but it was only the tube. A quick change and I was back on the road.
However, I was wondering if the irregular seating actually added strain to the tubes.